Jalisco and the Metropolitan Area of Guadalajara (MAG) have stood out due to their innovative approach in the management of the city. Their new metropolitan agenda aims to establish more coordinated, participatory, inclusive and effective governance processes, offering comprehensive solutions to the everyday challenges that the city and its inhabitants demand. However, we still face major challenges and opportunities that should be discussed to find feasible solutions with an innovative metropolitan approach. In order to do that, the Jalisco state government has established an agreement and joint agenda with UN-Habitat, whose strategy is to celebrate the International Forum on Innovation and Metropolitan Governance, along with other important initiatives. This world class event represents an opportunity to learn, present and exchange initiatives among cities around the world, with the purpose of understanding lessons learned on Metropolitan Governance and discussing the main actions to be taken, particularly in the MAG. This Forum will serve as a space to disseminate relevant contents of an existing public debate, mainly focused on the definition of the necessary measures to improve urban regions and cities. Furthermore, it will also actively contribute to the global agenda that UN-Habitat promotes, paving the way for the Third United Nations Conference of Human Settlements - HABITAT III, to be held in 2016 in Quito, Ecuador.